Embryo survival gene may fight range of diseases: study












HONG KONG (Reuters) – A gene that keeps embryos alive appears to control the immune system and determine how it fights chronic diseases like hepatitis and HIV, and autoimmune diseases like rheumatoid arthritis, scientists said on Monday.


Although the experts have only conducted studies on the gene Arih2 using mice, they hope it can be used as a target for drugs eventually to fight a spectrum of incurable diseases.












Lead author Marc Pellegrini at the Walter and Eliza Hall Institute of Medical Research in Australia said the gene appears to act like a switch, flipping the immune system on and off.


“If the gene is on, it dampens … the immune response. And if you switch it off, it greatly enhances immune responses,” Pellegrini said in a telephone interview.


“It is probably one of the few genes and pathways that is very targetable and could lead to a drug very quickly.”


Arih2 was first identified by another group of scientists in the fruit fly but it drew the interest of Pellegrini’s team because of its suspected links to the immune system.


In a paper published in Nature Immunology, Pellegrini and his team described how mice embryos died when the gene was removed.


Next, they removed the gene from adult mice and noticed how their immune systems were boosted for a short period of time. But it quickly went into an overdrive and started attacking the rodents’ own healthy cells, skin and organs.


“The mice survived for six weeks quite well. Then they started developing this very hyperactive immune responses and if you leave it for too long, it starts reacting against the body itself,” Pellegrini said.


Pellegrini and his colleagues hope that scientists can study the gene further and use it as a drug target to fight a large spectrum of diseases.


“It’s like an accelerator. In infectious diseases, you want to slam on the brakes on this gene, and for autoimmune diseases, you want to push the accelerator to make it work much harder to stop the whole immune response,” said Pellegrini.


“The more the gene works, the less of an immune response there is. And the less active the gene is, the more the immune response is.”


(Reporting by Tan Ee Lyn; Editing by Nick Macfie)


Sexual Health News Headlines – Yahoo! News


Read More..

World stocks muted ahead of meeting on Greece












BANGKOK (AP) — Asian stock markets rose modestly Monday after the unofficial start of the holiday shopping season in the U.S. topped expectations. But trading in Europe was subdued hours before finance ministers gathered yet again to discuss what to do about Greece.


The ministers of the 17 countries that use the euro are scheduled to meet in Brussels to try to reach an agreement on conditions that Greece must meet before the next installment of its emergency bailout loan can be disbursed. Athens faces bankruptcy without the cash.












In early European trading, Britain’s FTSE 100 fell 0.1 percent to 5,812.32. Germany‘s DAX was 0.1 percent down at 7,301.64. France‘s CAC-40 lost 0.3 percent to 3,519.75.


Wall Street, gearing up for its first full day of trading since last Wednesday, was set to fall. Dow Jones industrial futures lost 0.2 percent at 12,937 and S&P 500 futures shed 0.3 percent to 1,401.50. U.S. stocks rose on Friday after a half-day of trading.


Stocks in Asia fared better, posting some modest gains after what appeared to be a successful start to the traditional pre-Christmas U.S. shopping season.


Americans visited stores and websites in record numbers last Friday, the day after the Thanksgiving holiday that is dubbed “Black Friday” because U.S. retailers traditionally turn a profit as millions of Americans rush out to stores in search of gifts for Christmas and other celebrations.


Surveys showed a record 247 million shoppers visited stores and websites between Thursday and Sunday, up 9.2 percent from the year before.


Japan‘s Nikkei 225 index rose 0.2 percent to 9,388.94 while Australia‘s S&P/ASX 200 added 0.3 percent to 4,424.20. Benchmarks in Singapore, Taiwan, Indonesia, India and the Philippines also rose.


But South Korea‘s Kospi shed 0.2 percent to 1,908.15. Hong Kong‘s Hang Seng was sapped of momentum by lethargic mainland Chinese markets. The index lost 0.3 percent to 21,857.77. The Shanghai Composite Index was down 0.5 percent to 2,017.46. The smaller Shenzhen Composite Index lost 1.4 percent to 789.49.


Francis Lun, managing director of Lyncean Holdings in Hong Kong, said traders were shying away from mainland stock markets due to the failure of Chinese authorities to remove companies that fail to earn profits after three years.


A regulation exists to allow for a delisting after three years, but it is not enforced, Lun said.


“If you cannot weed out the losers, the stock market will be inundated with companies not doing anything,” he said. “The listed companies are out to grab money instead of earning a profit for shareholders.”


Among individual stocks, Japanese vehicle makers posted solid gains. Toyota Motor Corp. rose 1.7 percent. Nissan Motor Co. added 2.3 percent. Yamaha Motor Co. gained 2.1 percent.


Australia’s Sydney Airport rose 1.5 percent after announcing it has secured about $ 1.1 billion in new funds to repay existing debts and fund future spending.


Benchmark crude for January delivery was down 9 cents to $ 88.18 per barrel in electronic trading on the New York Mercantile Exchange. The contract rose 90 cents to finish at $ 88.28 per barrel on Friday.


In currencies, the euro fell to $ 1.2957 from $ 1.2971 late Friday in New York. The dollar fell to 82.01 yen from 82.40 yen. Earlier Monday, the dollar rose to 82.59 yen.


___


Follow Pamela Sampson on Twitter at http://twitter.com/pamelasampson


Economy News Headlines – Yahoo! News


Read More..

Prankster Replicates Facebook Users’ Profile Photos, Then Friends Targets [PICS]












1.


Image courtesy of Imgur, casinoroycasinoroy


Click here to view this gallery.












[More from Mashable: This App Curates Gifts From Startups for Your Trendy Friends]


Everyone has a knack for something. Reddit user CasinoRoy’s talent is creeping out strangers on Facebook, and perfectly replicating their profile photos.


[More from Mashable: Facebook to Slow Down After Move to HTTPS [VIDEO]]


The prankster searches for Facebook users with his name, and then recreates their profile photos by imitating their wardrobe and facial expression. When it’s all done, he sends the subject a friend request.


In total, CasinoRoy found eight people on Facebook with his name. He recently shared his hilarious project to Reddit, which garnered 20,000 views in four hours. The joker revealed on Reddit that only one person accepted his friend request. The relationship was short-lived. “He seemed genuinely creeped out and de-friended me shortly after,” he wrote.


What would you do if you found a perfect replica of your Facebook profile picture? Tell us in the comments below.


Image courtesy of Imgur, casinoroycasinoroy


This story originally published on Mashable here.


Social Media News Headlines – Yahoo! News


Read More..

“Downton Abbey” Renewed for fourth Season by ITV












LOS ANGELES (TheWrap.com) – “Downton Abbey” fans have something to be thankful for.


British network ITV has commissioned a fourth season of the hit historical drama, the network said Friday. The new season will consist of eight new episodes to premiere in fall 2013, with an extended episode for Christmas 2013. As with previous seasons, the opening and closing episodes will be feature-length.












“Downton Abbey” Season 4 will begin filming in February at Highclere Castle and Ealing Studios.


Noting that the upcoming season will see the inclusion of some new faces, “Downton Abbey” executive producer Gareth Neame said, “Viewers can look forward to more drama, comedy, love, hatred, jealousy, rivalry, ambition, despair and romance.”


Produced by NBC Universal’s Carnival Film & Television, the Emmy and Golden Glove-winning “Downton Abbey” airs on PBS in the U.S.


TV News Headlines – Yahoo! News


Read More..

Saudi royals, officials visit king in hospital after surgery












JEDDAH, Saudi Arabia (Reuters) – Senior Saudi royals and government officials have visited King Abdullah in hospital, state news agency SPA reported, a week after the monarch – believed to be in his late 80s – had surgery to tighten a ligament in his back.


The stability of the world’s biggest oil exporter and an important regional U.S. ally is of global concern as the kingdom holds more than a fifth of the world’s crude reserves and is a venue for millions of Muslim pilgrims every year.












SPA’s report on Saturday carried a photograph of officials and royals gathered inside the National Guard‘s King Abdulaziz Medical City in Riyadh, but did not say who was allowed to see the king or when he is expected to leave hospital.


The king was admitted for surgery on November 16 and an announcement from the Royal Court said that he had undergone a successful back operation that lasted for 11 hours. No photographs of Abdullah have been released.


Saudi analysts said on Saturday it was understandable that he would take time to recover, given his age.


Abdullah underwent a similar operation in October last year and had back surgery twice in the United States in 2010 for a herniated disc, after which spent three months outside Saudi Arabia recuperating.


After his back operation last year, Abdullah appeared on state television two days after his surgery and was released from hospital within five days of the operation.


Investors attributed Saudi stock market selling last week to worries over the king’s health. The benchmark index fell 3 percent in the trading week ending on Wednesday and fell 1.4 percent on Sunday after a 0.8 percent bounce on Saturday.


The crown has passed down a line of the sons of the kingdom’s founder King Abdulaziz Ibn Saud, who died in 1953.


Abdullah – who took power in 2005 – named his brother Prince Salman, 13 years his junior, heir apparent in June after the death of Crown Prince Nayef bin Abdulaziz.


Salman, who deputizes for the king, was shown on television last week meeting visiting U.S. officials. He also chaired the weekly cabinet meeting last Monday.


(Reporting by Asma Alsharif; Editing by Louise Ireland and Sami Aboudi)


Health News Headlines – Yahoo! News


Read More..

Catalonia election tests Spanish unity












BARCELONA, Spain (Reuters) – Voters in Spain’s Catalonia region go to the polls on Sunday and are likely to elect a pro-independence leader who will test Spanish unity at a time of deep economic crisis.


Opinion polls show two-thirds of voters in this region on the French border will cast ballots for parties, both rightist and leftist, that want Catalan independence from Spain.












Catalan President Artur Mas will likely win re-election since his conservative Convergence and Union party is forecast to take a majority, some 62 to 64 seats, in the 135-seat regional assembly, or Parliament.


Frustration over high unemployment and a deep recession have fueled a separatist resurgence in Catalonia, where polls show that for the first time more than half of the people want to break away from Spain.


Many Catalans believe their economy would be more prosperous on its own, complaining that a high portion of their taxes go to the central government in Madrid.


Mas, who adopted the independence cause in September after a massive street demonstration, campaigned on a promise to hold a referendum on secession.


If he carries through with the pledge, it will put him on a collision course with Madrid, where Prime Minister Mariano Rajoy will use the constitution to block a referendum.


“Catalonia has never faced elections this important,” Mas said at a campaign rally this week. He told supporters he wanted to be the last president of Catalonia within Spain.


A strong mandate for Mas and other Catalan independence leaders from the left will undermine Rajoy’s mission to persuade investors of Spain’s fiscal and political stability.


Spain’s deep recession and high public deficit have put it at the heart of the euro zone debt crisis and the government’s borrowing costs are painfully high.


Alicia Sanchez-Camacho, the candidate for Rajoy’s People’s Party in Catalonia has campaigned on a message that leaving Spain and the European Union would lead to economic disaster. The PP is vying to be the second biggest party in the Catalan Parliament with opinion polls forecasting it will win 17 seats.


“Don’t stay at home (on election day) if you don’t want them to kick us out of Spain and out of Europe,” she said at a campaign rally this week.


Polls open at 0800 GMT and close at 1900 GMT.


IDENTITY AND ECONOMY


In the rest of Spain the Catalan secession drive is viewed with disbelief and suspicion. Many Spaniards fear that if Catalonia moves to break away, the Basques could soon follow.


Like Basques, Catalans speak their own language and have always seen themselves as distinct from the rest of Spain.


The land of surrealist painter Salvador Dali and architect Antoni Gaudi prides itself on a regional character that blends pragmatism and idealism.


Home to car factories and banks that generate one fifth of Spain’s economic wealth, Catalonia also has one of the world’s most successful football clubs, FC Barcelona.


This year at Barcelona’s famous Camp Nou stadium fans started a new tradition. They chant “independence” at every game when the clock hits 17 minutes and 14 seconds – 1714 being the last year that Catalonia was under the Crown of Aragon before the Bourbon King Philip V united most of what is now Spain into one kingdom.


Catalan independence movements have waxed and waned over the centuries. Secessionism had been politically dead since Spain returned to democracy and gave its 17 autonomous regions significant self-governing power in the 1978 Constitution.


But now there is a widespread perception among Catalans that autonomy did not go far enough and the region is treated unfairly. Most supporters of Mas’s CiU party say the tax system drains resources from their region and that Madrid has refused to negotiate improvements.


Even though the Catalan treasury is broke and Mas has had to cut spending on schools and hospitals, many people in the region still blame Madrid for their woes.


“It’s like a marriage, when things are good then everything is fine, but when things go bad then you see if there really is any love there,” said Elias Banares, the 35-year-old owner of a shop that sells prams. He plans to vote for CiU.


The political mood has driven demand for “esteladas,” a flag that symbolises the independence movement, with a lone star against the red and yellow stripes of the official Catalan banner.


The “estelada,” once too politically risky for most Catalans to fly, now waves all over the Catalan capital, the Mediterranean port city of Barcelona.


“In two weeks we’ve sold more than in the last eight years. Amazing figures,” said Margarita Bascompte, owner of a family business that makes the flags in the city of Vic, in the heart of the most pro-independence province of Catalonia.


(Additional reporting by Nigel Davies and Elena Gyldenkerne; Editing by Jon Hemming)


Economy News Headlines – Yahoo! News


Read More..

Cricket-Australia v South Africa – second test scoreboard












ADELAIDE, Nov 24 (Reuters) – Scoreboard at the close of the


third day of the second test between Australia and South Africa












at Adelaide Oval on Saturday:


Australia won the toss and chose to bat


Australia first innings 550


South Africa first innings


G. Smith c Wade b Siddle 122


A. Petersen run out 54


H. Amla st Wade b Warner 11


J. Rudolph c Quiney b Lyon 29


AB de Villiers lbw b Siddle 1


F. du Plessis c Clarke b Hilfenhaus 78


D. Steyn c Ponting b Hilfenhaus 1


R. Kleinveldt b Hilfenhaus 0


J. Kallis c Wade b Clarke 58


M. Morkel b Lyon 6


I. Tahir not out 10


Extras (b-7, lb-2, w-3, nb-6) 18


Total: (all out, 124.3 overs) 388


Fall of wickets: 1-138 2-169 3-233 4-233 5-240 6-246 7-250


8-343 9-352 10-388


Bowling: B. Hilfenhaus 19.3-6-49-3, J. Pattinson 9.1-0-41-0


(nb-4, w-1) N. Lyon 44-7-91-2, P. Siddle 30.5-6-130-2 (nb-2), M.


Clarke 7-1-22-1, M. Hussey 1-0-7-0 (w-2), D. Warner 5-0-27-1, R.


Quiney 8-3-12-0


Australia second innings


D. Warner c Du Plessis b Kleinveldt 41


E. Cowan b Kleinveldt 29


R. Quiney c De Villiers b Kleinveldt 0


R. Ponting b Steyn 16


M. Clarke not out 9


P. Siddle c De Villiers b Morkel 1


M. Hussey 5


Extras (lb-7, nb-3) 10


Total (for five wickets, 32 overs) 111


Fall of wickets: 1-77 2-77 3-91 4-98 5-103


Still to bat: M. Wade, B. Hilfenhaus, J. Pattinson, N. Lyon.


Bowling: Steyn 10-4-28-1, Morkel 9-2-24-1, Kleinveldt


6-1-14-3 (nb-2), Tahir 7-1-38-0 (nb-1)


- -


Third test: WACA, Perth Nov. 30-Dec. 4


(Compiled by Ian Ransom; Editing by Alastair Himmer)


Australia / Antarctica News Headlines – Yahoo! News


Read More..

Larry Hagman dead at 81, portrayed notorious TV villain J.R. Ewing












(Reuters) – Larry Hagman, who created one of American television’s most supreme villains in the conniving, amoral oilman J.R. Ewing of “Dallas,” died on Friday, the Dallas Morning News reported. He was 81.


Hagman died at a Dallas hospital of complications from his battle with throat cancer, the newspaper said, quoting a statement from his family. He had suffered from liver cancer and cirrhosis of the liver in the 1990s after decades of drinking.












Hagman’s mother was stage and movie star Mary Martin and he became a star himself in 1965 on “I Dream of Jeannie,” a popular television sitcom in which he played Major Anthony Nelson, an astronaut who discovers a beautiful genie in a bottle.


Dallas,” which made its premiere on the CBS network in 1978, made Hagman a superstar. The show quickly became one of the network’s top-rated programs, built an international following and inspired a spin-off, imitators and a revival in 2012.


Dallas” was the night-time soap-opera story of a Texas family, fabulously wealthy from oil and cattle, and its plot brimmed with back-stabbing, double-dealing, family feuds, violence, adultery and other bad behavior.


In the middle of it all stood Hagman’s black-hearted J.R. Ewing – grinning wickedly in a broad cowboy hat and boots, plotting how to cheat his business competitors and cheat on his wife. He was the villain TV viewers loved to despise during the show’s 356-episode run from 1978 to 1991.


“I really can’t remember half of the people I’ve slept with, stabbed in the back or driven to suicide,” Hagman said of his character in Time magazine.


In his autobiography, “Hello Darlin’: Tall (and Absolutely True) Tales About My Life,” Hagman wrote that J.R. originally was not to be the focus of “Dallas” but that changed when he began ad-libbing on the set to make his character more outrageous and compelling.


‘WHO SHOT J.R.?’


To conclude its second season, the “Dallas” producers put together one of U.S. television’s most memorable episodes in which Ewing was shot by an unseen assailant. That gave fans months to fret over whether J.R. would survive and who had pulled the trigger. In the show’s opening the following season, it was revealed that J.R.’s sister-in-law, Kristin, with whom he had been having an affair, was behind the gun.


Hagman said an international publisher offered him $ 250,000 to reveal who had shot J.R. and he considered giving the wrong information and taking the money, but in the end, “I decided not to be so like J.R. in real life.”


The popularity of “Dallas” made Hagman one of the best-paid actors in television and earned him a fortune that even a Ewing would have coveted. He lost some of it, however, in bad oil investments before turning to real estate.


“I have an apartment in New York, a ranch in Santa Fe, a castle in Ojai outside of L.A., a beach house in Malibu and thinking of buying a place in Santa Monica,” Hagman said in a Chicago Tribune interview.


An updated “Dallas” series began in June 2012 on the TNT network with Hagman reprising his J.R. role with original cast members Linda Gray, who played J.R.’s long-suffering wife, Sue Ellen, and Patrick Duffy, who was his brother Bobby. The show was to focus on the sons of J.R. and Bobby.


Hagman had a wide eccentric streak. When he first met actress Lauren Bacall, he licked her arm because he had been told she did not like to be touched and he was known for leading parades on the Malibu beach and showing up at a grocery store in a gorilla suit. Above his Malibu home flew a flag with the credo “Vita Celebratio Est (Life Is a Celebration)” and he lived hard for many years.


In 1967, rock musician David Crosby turned him on to LSD, which Hagman said took away his fear of death, and Jack Nicholson introduced him to marijuana because Nicholson thought he was drinking too much.


Hagman had started drinking as a teenager and said he did not stop until the moment in 1992 when his doctor told him he had cirrhosis of the liver and could die within six months. Hagman wrote that for the past 15 years he had been drinking about four bottles of champagne a day, including while on the “Dallas” set.


LIVER TRANSPLANT


In July 1995, he was diagnosed with liver cancer, which led him to quit smoking, and a month later he underwent a liver transplant.


After giving up his vices, Hagman said he did not lose his zest for life.


“It’s the same old Larry Hagman,” he told a reporter. “He’s just a littler sober-er.”


Hagman was born on September 21, 1931, in Weatherford, Texas, and his father was a lawyer who dealt with the Texas oil barons Hagman would later come to portray. He was still a boy when his parents divorced and he went to Los Angeles with Martin, who would become a Broadway and Hollywood musical star.


Hagman eventually landed in New York to pursue acting, making his stage debut there in “The Taming of the Shrew.” In New York, he married Maj Axelsson in 1954 while they were in a production of “South Pacific. The marriage produced two children, Heidi and Preston.


Hagman served in the Air Force, spending five years in Europe as the director of USO shows, and on his return to New York he took a starring role in the daytime soap “The Edge of Night.” His breakthrough came in 1965 when he landed the “I Dream of Jeannie” role opposite Barbara Eden.


In his later years, Hagman became an advocate for organ transplants and an anti-smoking campaigner. He also was devoted to solar energy, telling the New York Times he had a $ 750,000 solar panel system at his Ojai estate, and made a commercial in which he portrayed a J.R. Ewing who had forsaken oil for solar power. He was a longtime member of the Peace and Freedom Party, a minor leftist organization in California.


Hagman told the Times that after death he wanted his remains to be “spread over a field and have marijuana and wheat planted and harvest it in a couple of years and then have a big marijuana cake, enough for 200 to 300 people. People would eat a little of Larry.”


(Writing by Bill Trott in Washington; Additional reporting by Alex Dobuszinkis in Los Angeles; Editing by Peter Cooney)


Celebrity News Headlines – Yahoo! News


Read More..

Four new cases of SARS-like virus found in Saudi, Qatar












LONDON (Reuters) – A new virus from the same family as SARS which sparked a global alert in September has now killed two people in Saudi Arabia, and total cases there and in Qatar have reached six, the World Health Organisation said.


The U.N. health agency issued an international alert in late September saying a virus previously unknown in humans had infected a Qatari man who had recently been in Saudi Arabia, where another man with the same virus had died.












On Friday it said in an outbreak update that it had registered four more cases and one of the new patients had died.


“The additional cases have been identified as part of the enhanced surveillance in Saudi Arabia (3 cases, including 1 death) and Qatar (1 case),” the WHO said.


The new virus is known as a coronavirus and shares some of the symptoms of SARS, or Severe Acute Respiratory Syndrome, which emerged in China in 2002 and killed around a 10th of the 8,000 people it infected worldwide.


Among the symptoms in the confirmed cases are fever, coughing and breathing difficulties.


Of the six laboratory-confirmed cases reported to WHO, four cases, including the two deaths, are from Saudi Arabia and two cases are from Qatar.


Britain’s Health Protection Agency, which helped to identify the new virus in September, said the newly reported case from Qatar was initially treated in October in Qatar but then transferred to Germany, and has now been discharged.


Coronaviruses are typically spread like other respiratory infections, such as flu, travelling in airborne droplets when an infected person coughs or sneezes.


The WHO said investigations were being conducted into the likely source of the infection, the method of exposure, and the possibility of human-to-human transmission of the virus.


“Close contacts of the recently confirmed cases are being identified and followed-up,” it said.


It added that so far, only the two most recently confirmed cases in Saudi Arabia were epidemiologically linked – they were from the same family, living in the same household.


“Preliminary investigations indicate that these two cases presented with similar symptoms of illness. One died and the other recovered,” the WHO’s statement said.


Two other members of the same family also suffered similar symptoms of illness, and one died and the other is recovering. But the WHO said laboratory test results on the fatality were still pending, and the person who is recovering had tested negative for the new coronavirus.


The virus has no formal name, but scientists at the British and Dutch laboratories where it was identified refer to it as “London1_novel CoV 2012″.


The WHO urged all its member states to continue surveillance for severe acute respiratory infections.


“Until more information is available, it is prudent to consider that the virus is likely more widely distributed than just the two countries which have identified cases,” it said.


(Editing by Alison Williams)


Health News Headlines – Yahoo! News


Read More..

Shoppers welcome early start to “Black Friday”












NEW YORK/BLOOMINGTON, Minnesota (Reuters) – Retailers declared their experiment with earlier store openings to kick off the holiday shopping season a success on Friday, with those new hours expected to be a Thanksgiving night staple for more retailers next year.


Stores such as Target Corp opened hours before midnight on Thursday to try to capture a bigger piece of the retail pie. The move seemed to bring out a different type of shopper than the usual one who grabs the “Black Friday” deals, analysts said.












That meant by Friday morning, some shoppers, like Christian Alcantara, 18, at a J.C. Penney Co Inc store in Queens, New York, had already made a lot of their purchases. J.C. Penney stuck to a more traditional 6 a.m. EST (1100 GMT) Friday opening.


“They should open earlier. I’ve been everywhere else and I’ve already shopped,” he said.


Shoppers like Alcantara are likely to force holdouts like J.C. Penney to move their post-Thanksgiving sales into Thursday night next year, said Liz Ebert, retail lead at consulting firm KPMG LLP.


“There will be pressure on them. There’ll be an expansion of it next year,” Ebert said.


Hard data on “Black Friday” store traffic will not come in until this weekend. But analysts said retailers who opened early brought in a non-traditional Black Friday shopper, with more families coming in together and buying more than just the “doorbuster” sale items.


“I’ve never seen parents bring so many kids on Black Friday,” Toys R Us Chief Executive Jerry Storch said.


The National Retail Federation expects sales during November and December to rise 4.1 percent this year, below last year’s 5.6 percent increase. That made store operators’ strategy important as they battled each other, rather than seeing a growing pie in a season when U.S. retailers can make a third of their annual sales and 40 to 50 percent of their profits.


“Retailers want them to buy now, they want to get that share of wallet early,” said Michael Appel, a director at consulting firm AlixPartners. He noticed that the Galleria Mall in White Plains, New York, was busy from midnight to 3 a.m., but that traffic, while still brisk, was less heavy by midmorning.


Shoppers used smartphones and tablets and a lot of research as they hit stores, a mobile phenomenon that started last year and seemed to be more prevalent this year.


Thom Blischok, chief retail strategist and a senior executive adviser with Booz & Company’s Retail practice, was waiting on line with one woman in Phoenix, who was shopping for a refrigerator. Using her mobile device, she found the appliance online for the same price and left the store without. She intended to buy it online instead.


“There’s a fundamental transformation of shopping,” he said.


Mobile devices account for 45 percent walmart.com traffic and online traffic coming from Walmart’s mobile app was three times bigger than last year, Joel Anderson, chief executive of Walmart.com, said.


Overall, online sales were up 20 percent versus the same period last year, through 3 p.m. EST (2000 GMT) on Friday, IBM said.


The National Retail Federation said 147 million people would shop Friday through Sunday, when deals are at their most eye-catching – down from 152 million the same weekend last year.


The NRF estimate did not account for Thursday shoppers and anecdotal evidence suggested retailers opening earlier may have cut into traffic on “Black Friday”, the traditional start of the holiday season that denotes the point when retailers in the past would turn a profit for the year.


“People seemed to be shopping quite a bit, although in talking to mall management, it seemed that traffic was not as busy as last year,” Deloitte retail analyst Ramesh Swamy said.


Retailers were also using technology better, allowing sales staff to match prices customers found online and having them use tablets as mobile “checkout stands” so buyers did not have to wait in line, a service consumers were quickly coming to expect.


“I even heard customers complaining about a retailer that didn’t have mobile checkout,” he said.


SAVING UP FOR CHRISTMAS SPREE


According to a Reuters/Ipsos poll, two-thirds of shoppers were planning to spend the same amount of money as last year or were unsure about plans, while 21 percent intended to spend less, and 11 percent planned to spend more.


“I definitely have more money this year,” said Amy Balser, 26, at the head of the line outside the Best Buy store in the Mall of America in Bloomington, Minnesota. “I definitely don’t think (the economy) has bounced back anywhere near as much as it needs to, but I see some improvement,” she said.


For others, Christmas is the focal point of their annual shopping.


“We cut back spending on birthdays and anniversaries so we’d have more for Christmas. We’ve adapted,” said Cheri Albus, 58, of Papillion, Nebraska, after shopping at J.C. Penney at Westroads Mall in Omaha.


Retail stocks rose in holiday-shortened trading on Friday, in line with gains across the market. Among the leaders, Wal-Mart ended up 1.9 percent and Macy’s Inc rose 1.8 percent.


STARTING EARLY


Across the country, store lines were long – in the hundreds or more in many places – with the move toward earlier opening hours appearing to help. By sunrise on Friday, it was commonplace, even at large stores in the major cities, to find many more staffers than shoppers.


While the shift to earlier openings was criticized by store employees and traditionalists because it pulled people away from families on the U.S. Thanksgiving holiday, many shoppers welcomed the chance to shop before midnight or in the early morning hours.


Some workers used the day to send a message.


OUR Walmart – a coalition of current and former Wal-Mart staff seeking better wages, benefits and working conditions – targeted Black Friday for action across the country after staging protests outside stores for months.


Nine protesters were arrested on misdemeanor charges after blocking a street outside a Walmart near Los Angeles, police said. Three of those arrested were Walmart workers, OUR Walmart said.


Wal-Mart Stores Inc’s U.S. discount stores, which have been open on Thanksgiving since 1988, offered some Black Friday deals at 8 p.m. on Thursday and special deals on certain electronics, such as Apple Inc iPads, at 10 p.m.


At the Macy’s store in Herald Square in Manhattan, the line at the Estee Lauder counter was four deep shortly after its midnight opening. The cosmetics department’s “morning specials” included free high-definition headphones with any fragrance purchase of $ 75 or more, and a set of six eye shadows for $ 10.


But for some people, cheap wasn’t cheap enough – like the Macy’s shopper who bought Calvin Klein shoes at 50 percent off but was still not satisfied.


“I was hoping for deeper discounts,” said Melissa Glascow, 35, of Brooklyn, New York.


That could actually be an intentional strategy to help retailers’ profits.


“It appears that manufacturers and retailers are making concerted efforts to drive margins, which may take some of the sales sizzle out of a traditionally big selling day/period, but should be positive to gross margins,” Credit Suisse analyst Gary Balter said in a note to clients.


Lines at Best Buy stores were similar to last year but the traffic to its website was “significantly” higher, Shawn Score, head of the company’s U.S. retail business, told Reuters.


(Additional reporting by Martinne Geller and Jochelle Mendonca in New York, Jessica Wohl and Nivedita Bhattacharjee in Chicago, Brad Dorfman in Milwaukee, Paul Ingram in Tucson, Arizona, Jason McLure in Littleton, New Hampshire, and Barbara Liston in Orlando, Florida; Writing by Brad Dorfman and Ben Berkowitz; Editing by Nick Macfie, David Holmes, Jeffrey Benkoe, Dale Hudson and Leslie Gevirtz)


Business News Headlines – Yahoo! News


Read More..